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History

June, 2009 Phase II clinical study of CBP501 + Pemetrexed + Cisplatin in patients with Non-Small Cell Lung Cancer initiated in U.S.
June, 2009 Preclinical study of CBS9106 initiated.
November, 2008 Phase II clinical study of CBP501 + Pemetrexed + Cisplatin in patients with Malignant Pleural Mesothelioma initiated in U.S.
May, 2008 Phase I clinical study of CBP501 + Pemetrexed + Cisplatin has been initiated in U.S.
April, 2008 Patent application for low molecular compound CBS9100 series
March, 2007 CanBas and Takeda to Sign the Collaboration Agreement for Investigational Compounds for Treatment of Cancer.
October, 2007 Phase 1 clinical study of CBP501 (combination use with Cisplatin ) was initiated in US.
April, 2007 Patent approval for CBS2400 series(US).
February, 2006 Patent approval for CBP501(US).
May, 2006 Phase 1 clinical study of CBP501 (monotherapy) was initiated in US.
April, 2005 Patent for the screening method of the cell cycle G2 checkpoint issued by USPTO.
June, 2005 Patent application for low molecular compound CBS2400 series
Jan, 2003 Patent application for CBP501, candidate compound of anticancer drug that optimized TAT-S216.
January, 2003 1st Scientific Advisory Board (SAB) meeting.
September, 2002 US patent/PCT application for drug screening method, original peptide TAT-S216.
January, 2000 Founded in Toyota, Aichi Pref, for the purpose of research and development of new anticancer drug.

December, 1998 The original peptide considered to abrogate G2 checkpoint specifically Success in TAT-S216 design.
January, 1997 Contribution of paper to Nature, a science magazine, to present that oncogene Hox11 abrogates G2 checkpoint.
In around 1994 Conception of possibility to develop anticancer drug by G2 checkpoint abrogation during the analysis of Hox11 carcinogenic mechanism

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