
Invited Publication
- Compounds that Abrogate the G2 Checkpoint
"Checkpoint Responses in Cancer Therapy"
Dai, Wei (Ed.), Humana Press, 2008: 117-133
- G2 checkpoint abrogators as anticancer drugs
Minireview, Mol Cancer Ther 2004 3: 513-519
Peer-Reviewed Publication (一部)
- Cell cycle phenotype-based optimization of G2-abrogating peptides yields CBP501 with a unique mechanism of action at the G2 checkpoint
Mol. Cancer Ther. 2007 6: 147-153
- Cdc25C interacts with PCNA at G2/M transition
Oncogene, Vol.21, 1717・1726, 2002
- Involvement of the Interaction between p21 and PCNA for the maintenance of G2/M arrest after DNA damage.
J Biol Chem, Vol.276, No.46, 42971-42977, 2001
- Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation.
Cancer Res., 59, 5887-5891, 1999
- Hox11 interacts with PP1 and PP2A and disrupts a G2 check point.
Nature, 385, 454-458, 1997
Abstracts(一部)
- Phase I studies of CBP501, a novel G2 checkpoint abrogator, alone and combined with cisplatin (CDDP) in advanced solid tumor patients (pts).
2008 ASCO Annual Meeting, Chicago, May 30 - June 3, 2008
- CBP501, a novel cell cycle G2 checkpoint abrogator. Preliminary results of the initial phase I and pharmacokinetic (PK) / pharmacodynamic (PD) study in patients (pts) with advanced solid tumors.
18th EORTC-NCI-AACR, Prague, November 7-10, 2006
- Pre-clinical analysis of CBP501, a novel G2 checkpoint abrogator.
AACR 94th Annual Meeting, Toronto, April, 2003
(The meeting had been postponed to July at Washington D.C.)
- Targeting G2 checkpoint by a novel peptide CBP501
Keystone symposia, "Molecular Targets for Cancer Therapy", Banff, 3/19-24, 2003
- Selective cancer cell killing by a novel G2 checkpoint abrogating peptide.
<2001 AACR Scholar-In-Training Award>
AACR 92st Annual Meeting, New Orleans, Mar, 2001
- Anti-cancer therapy by specific abrogation of DNA damage-induced cell cycle G2 checkpoint using Chk2 inhibiting peptides.
Keystone Symposia, Cell Cycle 2001,
Taos, Jan 9-14. 2001
- Killing cancer cells by targeted abrogation of cell cycle G2 checkpoint by peptide antagonists against Chk1/Cds1 kinases.
AACR 91st Annual Meeting, San Francisco, April 1-5, 2000
- Cdc25C transiently replaces Wee1HU in PCNA/Cdc2/Cyclin B complex at the G2/M transition.
Keystone Symposia, "Cancer, Cell cycle and Therapeutics", Jan8-13th, 2000
- Sensitization of cancer cells to DNA damage-induced cell death by specific cell cycle G2 checkpoint abrogation.
Keystone Symposia, "Cancer, Cell cycle and Therapeutics", Jan8-13th, 2000
- Regulation of the genes involved in the G2 checkpoint in the G2 arrested Jurkat.
Keystone Symposia "The cell cycle"
Keystone, Cololado, Mar 27-Apr 2, 1998
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